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Intermittent Hypoxia: Mechanisms of Action and Some Applications to Bronchial Asthma Treatment

T.V. Serebrovskaya, R.J. Swanson, E.E. Kolesnikova Bogomoletz Institute of Physiology, Kiev, Ukraine and Old Dominion University, Norfolk VA, USA

Ukrainian and Russian scientists have developed a new concept for the beneficial use of adaptation to artificial intermittent hypoxia in treating of many diseases. The basic mechanisms underlying intermittent hypoxic training were elaborated mainly in three areas: regulation of respiration, free radical production and mitochondrial respiration.

Twenty-year experience of the application of intermittent hypoxic therapy for the treatment of chronic obstructive bronchitis and bronchial asthma allows affirming that the adaptation to this kind of hypoxia causes a significant improvement of the clinical picture of even a complete recovery.

The absence of negative side effects, typically observed during drug therapy, and the stimulation of organism's general, nonspecific resistance, makes the hypoxic therapy a treatment with a future. Special note on intermittent hypoxic training in industrial health care for the purpose of prophylaxis and treatment of professional diseases.

(Click here to view the study.)[http://www.hyperbaricoxygentherapy.org.uk/resources/docs/Intermittent_Hypoxia-_Mechanisms_of_Action_and_some_Applications_to_Bronchial_Asthma_Treatment.pdf]

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