Research & Guidance

N. Epifanova, A. Koukchina, I. Epifanov.
Sklifosovsky Research Institute for Emergency Medicine. Moscow, Russia
European Psychiatry, Vol 15, no. S2, pp 440-441 (octobre 2000)

Summary:

Long-term drug addiction is associated with homeostasis impairments, toxic encephalopathy, somatic pathology and often leads to fatal outcomes due to drug abuse. The experimental study of toxic brain edema by using light microscopy and found that hyperbaric oxygenation (HBO) activates the rhybonucleoproteid syntesis in the neurons, intensifies proliferative glial reactions, and thus, improves the cerebral metabolism. In this connection, the use of HBO in the treatment of emergency conditions associated with drug abuse is well-grounded from the point of pathogenesis.

HBO treatment to prevent the development persistent neuropsychologic disturbances, and to decrease the incidence of delayed neuropsychological sequelae. The use of HBO posing detoxication, antihypoxic and metabolic effects in the complex treatment of drug - addiction to improve the outcomes. Thus, HBO may be used as a method of a metabolic brain protect.

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